Browsing HMS Scholarly Articles by Author "Fang, Yanshan"
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Cooperative Interaction between Phosphorylation Sites on PERIOD Maintains Circadian Period in Drosophila
Garbe, David S.; Fang, Yanshan; Zheng, Xiangzhong; Sowcik, Mallory; Anjum, Rana; Gygi, Steven P.; Sehgal, Amita (Public Library of Science, 2013)Circadian rhythms in Drosophila rely on cyclic regulation of the period (per) and timeless (tim) clock genes. The molecular cycle requires rhythmic phosphorylation of PER and TIM proteins, which is mediated by several ...