Browsing HMS Scholarly Articles by Keyword "Microbial Metabolism"
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The Ability of Flux Balance Analysis to Predict Evolution of Central Metabolism Scales with the Initial Distance to the Optimum
(Public Library of Science, 2013)The most powerful genome-scale framework to model metabolism, flux balance analysis (FBA), is an evolutionary optimality model. It hypothesizes selection upon a proposed optimality criterion in order to predict the set of ... -
Catecholate Siderophores Protect Bacteria from Pyochelin Toxicity
(Public Library of Science, 2012)Background: Bacteria produce small molecule iron chelators, known as siderophores, to facilitate the acquisition of iron from the environment. The synthesis of more than one siderophore and the production of multiple ... -
Structural Characterization of Pandoraea pnomenusa B-356 Biphenyl Dioxygenase Reveals Features of Potent Polychlorinated Biphenyl-Degrading Enzymes
(Public Library of Science, 2013)The oxidative degradation of biphenyl and polychlorinated biphenyls (PCBs) is initiated in Pandoraea pnomenusa B-356 by biphenyl dioxygenase \((BPDO_{B356})\). \(BPDO_{B356}\), a heterohexameric \((αβ)_3\) Rieske oxygenase ...