Browsing HMS Scholarly Articles by Keyword "Clinical Trial Biology"

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    • Pain Facilitation Brain Regions Activated by Nalbuphine Are Revealed by Pharmacological fMRI 

      Gear, Robert; Becerra, Lino Renan; Upadhyay, Jaymin; Bishop, James; Wallin, Diana; Pendse, Gautam; Levine, Jon; Borsook, David (Public Library of Science, 2013)
      Nalbuphine, an agonist-antagonist kappa-opioid, produces brief analgesia followed by enhanced pain/hyperalgesia in male postsurgical patients. However, it produces profound analgesia without pain enhancement when ...