Browsing HMS Scholarly Articles by Keyword "Cost-Effectiveness Analysis"

Now showing items 1-8 of 8

    • The Clinical and Economic Impact of Point-of-Care CD4 Testing in Mozambique and Other Resource-Limited Settings: A Cost-Effectiveness Analysis 

      Hyle, Emily P.; Jani, Ilesh V.; Lehe, Jonathan; Su, Amanda E.; Wood, Robin; Quevedo, Jorge; Losina, Elena; Bassett, Ingrid V.; Pei, Pamela P.; Paltiel, A. David; Resch, Stephen; Freedberg, Kenneth A.; Peter, Trevor; Walensky, Rochelle P. (Public Library of Science, 2014)
      Background: Point-of-care CD4 tests at HIV diagnosis could improve linkage to care in resource-limited settings. Our objective is to evaluate the clinical and economic impact of point-of-care CD4 tests compared to ...

    • Clinical Impact and Cost-Effectiveness of Expanded Voluntary HIV Testing in India 

      Venkatesh, Kartik K.; Becker, Jessica E.; Kumarasamy, Nagalingeswaran; Nakamura, Yoriko M.; Mayer, Kenneth H.; Losina, Elena; Swaminathan, Soumya; Flanigan, Timothy P.; Walensky, Rochelle P.; Freedberg, Kenneth A. (Public Library of Science, 2013)
      Background: Despite expanding access to antiretroviral therapy (ART), most of the estimated 2.3 to 2.5 million HIV-infected individuals in India remain undiagnosed. The questions of whom to test for HIV and at what frequency ...

    • Cost-Effectiveness Analysis: Risk Stratification of Nonalcoholic Fatty Liver Disease (NAFLD) by the Primary Care Physician Using the NAFLD Fibrosis Score 

      Tapper, Elliot B.; Hunink, M. G. Myriam; Afdhal, Nezam H.; Lai, Michelle; Sengupta, Neil (Public Library of Science, 2016)
      Background: The complications of Nonalcoholic Fatty Liver Disease (NAFLD) are dependent on the presence of advanced fibrosis. Given the high prevalence of NAFLD in the US, the optimal evaluation of NAFLD likely involves ...

    • The Cost-Effectiveness of Tuberculosis Preventive Therapy for HIV-Infected Individuals in Southern India: A Trial-Based Analysis 

      Pho, Mai T.; Swaminathan, Soumya; Kumarasamy, Nagalingeswaran; Losina, Elena; Ponnuraja, C.; Uhler, Lauren M.; Scott, Callie A.; Mayer, Kenneth Hugh; Freedberg, Kenneth Alan; Walensky, Rochelle P. (Public Library of Science, 2012)
      Background: Regimens for isoniazid-based preventive therapy (IPT) for tuberculosis (TB) in HIV-infected individuals have not been widely adopted given concerns regarding efficacy, adherence and drug resistance. Further, ...

    • Global Patterns of QALY and DALY Use in Surgical Cost-Utility Analyses: A Systematic Review 

      Rios-Diaz, Arturo J.; Lam, Jimmy; Ramos, Margarita S.; Moscoso, Andrea V.; Vaughn, Patrick; Zogg, Cheryl K.; Caterson, Edward J. (Public Library of Science, 2016)
      Background: Surgical interventions are being increasingly recognized as cost-effective global priorities, the utility of which are frequently measured using either quality-adjusted (QALY) or disability-adjusted (DALY) life ...

    • HIV Cure Strategies: How Good Must They Be to Improve on Current Antiretroviral Therapy? 

      Sax, Paul E.; Sypek, Alexis; Berkowitz, Bethany K.; Morris, Bethany L.; Losina, Elena; Paltiel, A. David; Kelly, Kathleen A.; Seage, George R.; Walensky, Rochelle P.; Weinstein, Milton C.; Eron, Joseph; Freedberg, Kenneth A. (Public Library of Science, 2014)
      Background: We examined efficacy, toxicity, relapse, cost, and quality-of-life thresholds of hypothetical HIV cure interventions that would make them cost-effective compared to life-long antiretroviral therapy (ART). ...

    • Mobile HIV Screening in Cape Town, South Africa: Clinical Impact, Cost and Cost-Effectiveness 

      Bassett, Ingrid V.; Govindasamy, Darshini; Erlwanger, Alison S.; Hyle, Emily P.; Kranzer, Katharina; van Schaik, Nienke; Noubary, Farzad; Paltiel, A. David; Wood, Robin; Walensky, Rochelle P.; Losina, Elena; Bekker, Linda-Gail; Freedberg, Kenneth A. (Public Library of Science, 2014)
      Background: Mobile HIV screening may facilitate early HIV diagnosis. Our objective was to examine the cost-effectiveness of adding a mobile screening unit to current medical facility-based HIV testing in Cape Town, South ...

    • Placing a Price on Medical Device Innovation: The Example of Total Knee Arthroplasty 

      Suter, Lisa G.; Paltiel, A. David; Rome, Benjamin Newman; Solomon, Daniel Hal; Thornhill, Thomas Stone; Abrams, Stanley K.; Katz, Jeffrey Neil; Losina, Elena (Public Library of Science, 2013)
      Background: Total knee arthroplasty (TKA) is common, effective, and cost-effective. Innovative implants promising reduced long-term failure at increased cost are under continual development. We sought to define the implant ...