Browsing HMS Scholarly Articles by Keyword "connective tissue disease"

Now showing items 1-1 of 1

    • Targeted Induction of Endoplasmic Reticulum Stress Induces Cartilage Pathology 

      Rajpar, M. Helen; McDermott, Ben; Kung, Louise; Eardley, Rachel; Knowles, Lynette; Heeran, Mel; Bateman, John F.; Poulsom, Richard; Arvan, Peter; Kadler, Karl E.; Briggs, Michael D.; Boot-Handford, Raymond P.; Thornton, David James; Wilson, Richard (Public Library of Science, 2009)
      Pathologies caused by mutations in extracellular matrix proteins are generally considered to result from the synthesis of extracellular matrices that are defective. Mutations in type X collagen cause metaphyseal chondrodysplasia ...