Browsing by Author "Yuan, Quan"

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    • FGF23 Deficiency Leads to Mixed Hearing Loss and Middle Ear Malformation in Mice 

      Lysaght, Andrew C.; Yuan, Quan; Fan, Yi; Kalwani, Neil; Caruso, Paul; Cunnane, MaryBeth; Lanske, Beate; Stanković, Konstantina M. (Public Library of Science, 2014)
      Fibroblast growth factor 23 (FGF23) is a circulating hormone important in phosphate homeostasis. Abnormal serum levels of FGF23 result in systemic pathologies in humans and mice, including renal phosphate wasting diseases ...

    • FGF23 neutralization improves bone quality and osseointegration of titanium implants in chronic kidney disease mice 

      Sun, Ningyuan; Guo, Yuchen; Liu, Weiqing; Densmore, Michael; Shalhoub, Victoria; Erben, Reinhold G.; Ye, Ling; Lanske, Beate; Yuan, Quan (Nature Publishing Group, 2015)
      Chronic kidney disease (CKD) is a worldwide health problem. Serum levels of FGF23, a phosphaturic hormone, increase at the earliest stages of CKD, and have been found to be independently associated with the mortality and ...

    • Vitamin D Supplementation Enhances the Fixation of Titanium Implants in Chronic Kidney Disease Mice 

      Liu, Weiqing; Zhang, Shiwen; Zhao, Dan; Zou, Huawei; Sun, Ningyuan; Liang, Xing; Dard, Michel; Lanske, Beate; Yuan, Quan (Public Library of Science, 2014)
      Vitamin D (Vit D) deficiency is a common condition in chronic kidney disease (CKD) patients that negatively affects bone regeneration and fracture healing. Previous study has shown that timely healing of titanium implants ...