Now showing items 1-3 of 3

    • Diazoxide amelioration of myocardial injury and mitochondrial damage during cardiac surgery 

      McCully, James Donald; Wakiyama, Hidetaka; Cowan, Douglas Burr; Federman, Micheline; Parker, Robert A; Levitsky, Sidney (Elsevier BV, 2002)
      Background Recently, we have shown that the selective opening of mitochondrial ATP-sensitive potassium channels with diazoxide significantly decreases myocardial injury. The purpose of this study was to determine the ...
    • Differential Expression of Collagen Type V and XI ?-1 in Human Ascending Thoracic Aortic Aneurysms 

      Toumpoulis, Ioannis K.; Oxford, Julia Thom; Cowan, Douglas Burr; Anagnostopoulos, Constantine E.; Rokkas, Chris K.; Chamogeorgakis, Themistocles P.; Angouras, Dimitrios C.; Shemin, Richard J.; Navab, Mohamad; Ericsson, Maria; Federman, Micheline; Levitsky, Sidney; McCully, James Donald (Elsevier BV, 2009)
      Background The molecular mechanisms leading to ascending thoracic aortic aneurysms (ATAAs) remain unknown. We hypothesized that alterations in expression levels of specific fibrillar collagens occur during the aneurysmal ...
    • Reduction and Redistribution of Gap and Adherens Junction Proteins After Ischemia and Reperfusion 

      Tansey, Erin E.; Kwaku, Kevin F.; Hammer, Peter; Cowan, Douglas Burr; Federman, Micheline; Levitsky, Sidney; McCully, James Donald (Elsevier BV, 2006)
      Background Previous studies have demonstrated that alterations in myocardial structure, consistent with tissue and sarcomere disruption as well as myofibril dissociation, occur after myocardial ischemia and reperfusion. ...