Browsing by Author "Heath, Robert John William"
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Bacterial and Host Determinants of MAL Activation upon EPEC Infection: The Roles of Tir, ABRA, and FLRT3
Heath, Robert John William; Leong, John M.; Visegrády, Balázs; Machesky, Laura M.; Xavier, Ramnik (Public Library of Science, 2011)Infection of host cells by pathogenic microbes triggers signal transduction pathways leading to a multitude of host cell responses including actin cytoskeletal re-arrangements and transcriptional programs. The diarrheagenic ... -
Control and Manipulation of Pathogens with an Optical Trap for Live Cell Imaging of Intercellular Interactions
Tam, Jenny M.; Castro, Carlos E.; Heath, Robert John William; Cardenas, Michael L.; Xavier, Ramnik; Lang, Matthew J.; Vyas, Jatin Mahesh (Public Library of Science, 2010)The application of live cell imaging allows direct visualization of the dynamic interactions between cells of the immune system. Some preliminary observations challenge long-held beliefs about immune responses to microorganisms; ...