Browsing by Author "García-Añoveros, Jaime"

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    • Mutant Sodium Channel for Tumor Therapy 

      Tannous, Bakhos A.; Christensen, Adam P.; Pike, Lisa; Wurdinger, Thomas; Perry, Katherine F.; Saydam, Okay; Jacobs, Andreas H.; García-Añoveros, Jaime; Weissleder, Ralph; Sena-Esteves, Miguel; Corey, David P.; Breakefield, Xandra O. (Elsevier (Cell Press), 2009)
      Viral vectors have been used to deliver a wide range of therapeutic genes to tumors. In this study, a novel tumor therapy was achieved by the delivery of a mammalian brain sodium channel, ASIC2a, carrying a mutation that ...