Browsing by Author "Widlund, Hans"
Now showing items 1-2 of 2
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Dual Suppression of the Cyclin-Dependent Kinase Inhibitors CDKN2C and CDKN1A in Human Melanoma
Jalili, Ahmad; Wagner, Christine; Pashenkov, Mikhail; Pathria, Gaurav; Mertz, Kirsten D.; Widlund, Hans R.; Lupien, Mathieu; Brunet, Jean- Philippe; Golub, Todd R.; Stingl, Georg; Fisher, David Erich; Ramaswamy, Sridhar; Wagner, Stephan N. (Oxford University Press, 2012)Resistance to BRAFV600E inhibitors is associated with reactivation of mitogen-activated protein kinase (MAPK) signaling at different levels in melanoma. To identify downstream effectors of MAPK signaling that could be used ... -
RSK Activation of Translation Factor eIF4B Drives Abnormal Increases of Laminin γ2 and MYC Protein during Neoplastic Progression to Squamous Cell Carcinoma
Degen, Martin; Barron, Patricia; Natarajan, Easwar; Widlund, Hans R.; Rheinwald, James G. (Public Library of Science, 2013)Overexpression of the basement membrane protein Laminin γ2 (Lamγ2) is a feature of many epidermal and oral dysplasias and all invasive squamous cell carcinomas (SCCs). This abnormality has potential value as an immunohistochemical ...