Browsing by Author "Lee, Byung-Hoon"

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    • USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites 

      Lee, Byung-Hoon; Lu, Ying; Prado, Miguel A.; Shi, Yuan; Tian, Geng; Sun, Shuangwu; Elsasser, Suzanne; Gygi, Steven P.; King, Randall W.; Finley, Daniel J. (Springer Nature, 2016)
      USP14 is a major regulator of the proteasome and one of three proteasome-associated deubiquitinating enzymes1-9. Its effects on protein turnover are substrate specific, for unknown reasons. We report that USP14 shows a ...