Browsing by Keyword "E-selectin"
Now showing items 1-3 of 3
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Complementary targeting of liposomes to IL-1? and TNF-? activated endothelial cells via the transient expression of VCAM1 and E-selectin
(Elsevier BV, 2011)Inflammation is in part defined by the transient upregulation of cell adhesion molecules on the surface of endothelial cells (ECs) in response to cytokines. We hypothesized that liposomes with a complementary surface ... -
Neuregulin1-β Decreases IL-1β -Induced Neutrophil Adhesion to Human Brain Microvascular Endothelial Cells
(Springer Nature, 2014)Neuroinflammation contributes to the pathophysiology of diverse diseases including stroke, traumatic brain injury, Alzheimer's Disease, Parkinson's Disease, and multiple sclerosis, resulting in neurodegeneration and loss ... -
Vascular E-selectin expression correlates with CD8 lymphocyte infiltration and improved outcome in Merkel cell carcinoma
(2013)Merkel cell carcinoma (MCC) is an aggressive, polyomavirus-linked skin cancer. While CD8 lymphocyte infiltration into the tumor is strongly correlated with improved survival, these cells are absent or sparse in most MCCs. ...