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Chen, Zhunan

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Chen

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Zhunan

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Chen, Zhunan

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  • Publication

    Molecular and Circuit Mechanisms of Insulin Signaling in Caenorhabditis elegans

    (2014-02-25) Chen, Zhunan; Zhang, Yun; Pierce, Naomi; Hoekstra, Hopi; Hunter, Craig; Uchida, Naoshige; Zhang, Yun

    Insulin signaling is highly conserved across animals, and is known for its ubiquitous function in all aspects of animal physiology. Despite its relatively well-studied role in metabolism and energy expenditure, how it is involved in learning and memory remains a mystery, due to the complex nature of the nervous system. In this thesis, I have used C. elegans, a tractable model organism with a sophisticated behavioral repertoire, to investigate molecular and cellular mechanisms of insulin signaling in learning.