Publication: Molecular and Circuit Mechanisms of Insulin Signaling in Caenorhabditis elegans
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2014-02-25
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Chen, Zhunan. 2014. Molecular and Circuit Mechanisms of Insulin Signaling in Caenorhabditis elegans. Doctoral dissertation, Harvard University.
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Abstract
Insulin signaling is highly conserved across animals, and is known for its ubiquitous function in all aspects of animal physiology. Despite its relatively well-studied role in metabolism and energy expenditure, how it is involved in learning and memory remains a mystery, due to the complex nature of the nervous system. In this thesis, I have used C. elegans, a tractable model organism with a sophisticated behavioral repertoire, to investigate molecular and cellular mechanisms of insulin signaling in learning.
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Keywords
Biology, C. elegans, Insulin, Learning Behavior
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