(Springer Science and Business Media LLC, 2021-03-09) Mills, Evanna; Xiao, Haopeng; Chouchani, Edward
In response to cold stress, mammals release norepinephrine from the sympathetic nervous system to elevate thermogenesis in brown adipose tissue (BAT) in order to maintain body temperature. This study reveals that the protein AIDA connects sympathetic input, reactive oxygen species, and uncoupling protein 1-mediated adaptive thermogenesis in BAT.
