(2014-06-06) Rothchild, Alissa Chen; Behar, Samuel Maurice; Winau, Florian; Starnbach, Michael; Cooper, Andrea; Brenner, Michael
Despite effective antibiotics, Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, still infects nearly one-third of the world's population. While key immune factors including CD4+ T cells and IFNg production have been identified, there are still many antimicrobial mechanisms yet to be explored. Here we characterized the role of invariant natural killer T (iNKT) cells and GM-CSF during Mtb infection.
