Person: Ji, Changwei
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Ji, Changwei
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Publication DNA Self-Assembly of Targeted Near-Infrared-Responsive Gold Nanoparticles for Cancer Thermo-Chemotherapy
(WILEY-VCH Verlag, 2012) Xiao, Zeyu; Ji, Changwei; Shi, Jinjun; Pridgen, Eric M; Frieder, Jillian; Farokhzad, OmidTargeted Cancer Therapy: Inspired by the ability of DNA hybridization, a targeted near-infrared (NIR) light-responsive delivery system has been developed through simple DNA self-assembly (PEG=polyethylene glycol). This DNA-based platform shows the ability of releasing therapeutics upon near-infrared irradiation, and remarkable targeted thermo- and chemotherapeutic efficacy in vitro and in vivo.