Publication: Blood Banking in Living Droplets
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Date
2011
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Public Library of Science
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Samot, Josh, Sangjun Moon, Lei Shao, Xiaohui Zhang, Feng Xu, YoungSeok Song, Hasan Onur Keles, Laura Matloff, Jordan Markel, and Utkan Demirci. 2011. Blood banking in living droplets. PLoS ONE 6(3): e17530.
Abstract
Blood banking has a broad public health impact influencing millions of lives daily. It could potentially benefit from emerging biopreservation technologies. However, although vitrification has shown advantages over traditional cryopreservation techniques, it has not been incorporated into transfusion medicine mainly due to throughput challenges. Here, we present a scalable method that can vitrify red blood cells in microdroplets. This approach enables the vitrification of large volumes of blood in a short amount of time, and makes it a viable and scalable biotechnology tool for blood cryopreservation.
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biology, biotechnology, bioengineering, tissue engineering, engineering, biomedical engineering, medicine, critical care and emergency medicine, hematology, transfusion medicine
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