Publication: Immunovirotherapy for the treatment of glioblastoma
| dash.depositing.author | Cheema, Tooba A | en_US |
| dash.license | LAA | en_US |
| dc.contributor.author | Cheema, Tooba A | |
| dc.contributor.author | Fecci, Peter | |
| dc.contributor.author | Ning, Jianfang | |
| dc.contributor.author | Rabkin, Samuel | |
| dc.date.accessioned | 2014-03-11T13:53:42Z | |
| dc.date.available | 2014-03-11T13:53:42Z | |
| dc.date.issued | 2014 | en_US |
| dc.description.abstract | We have recently described a new murine model of glioblastoma, generated by the implantation of syngeneic glioblastoma stem cells into immunocompetent mice, that recapitulates the salient histopathological and immunological features of the human disease. We employed this model to demonstrate the multifaceted activity of an oncolytic herpes simplex virus genetically modified to express interleukin-12, G47∆-IL12. | en |
| dc.description.version | Version of Record | en |
| dc.identifier.citation | Cheema, Tooba A, Peter E Fecci, Jianfang Ning, and Samuel D Rabkin. 2014. “Immunovirotherapy for the treatment of glioblastoma.” Oncoimmunology 3 (1): e27218. doi:10.4161/onci.27218. http://dx.doi.org/10.4161/onci.27218. | en |
| dc.identifier.doi | 10.4161/onci.27218 | * |
| dc.identifier.issn | 2162-4011 | en |
| dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:11879877 | |
| dc.language.iso | en_US | en |
| dc.publisher | Landes Bioscience | en |
| dc.relation.hasversion | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929360/pdf/ | en |
| dc.relation.isversionof | doi:10.4161/onci.27218 | en |
| dc.relation.journal | Oncoimmunology | en |
| dc.subject | cancer stem cells | en |
| dc.subject | glioma | en |
| dc.subject | herpes simplex virus | en |
| dc.subject | interleukin-12 | en |
| dc.subject | oncolytic virus | en |
| dc.subject | Treg | en |
| dc.title | Immunovirotherapy for the treatment of glioblastoma | en |
| dc.type | Journal Article | en_US |
| dspace.entity.type | Publication | |
| oaire.licenseCondition | LAA | en_US |
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