Publication: Directing traffic on DNA—How transcription factors relieve or induce transcriptional interference
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Date
2017
Published Version
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Publisher
Taylor & Francis
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Citation
Hao, Nan, Adam C. Palmer, Ian B. Dodd, and Keith E. Shearwin. 2017. “Directing traffic on DNA—How transcription factors relieve or induce transcriptional interference.” Transcription 8 (2): 120-125. doi:10.1080/21541264.2017.1285851. http://dx.doi.org/10.1080/21541264.2017.1285851.
Research Data
Abstract
ABSTRACT Transcriptional interference (TI) is increasingly recognized as a widespread mechanism of gene control, particularly given the pervasive nature of transcription, both sense and antisense, across all kingdoms of life. Here, we discuss how transcription factor binding kinetics strongly influence the ability of a transcription factor to relieve or induce TI.
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Keywords
convergent promoters, dislodgement, roadblock, DNA-binding kinetics, transcriptional interference
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