Publication: Glucose‐Sensitive Hydrogel Optical Fibers Functionalized with Phenylboronic Acid
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Date
2017
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John Wiley and Sons Inc.
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Yetisen, A. K., N. Jiang, A. Fallahi, Y. Montelongo, G. U. Ruiz‐Esparza, A. Tamayol, Y. S. Zhang, et al. 2017. “Glucose‐Sensitive Hydrogel Optical Fibers Functionalized with Phenylboronic Acid.” Advanced Materials (Deerfield Beach, Fla.) 29 (15): 1606380. doi:10.1002/adma.201606380. http://dx.doi.org/10.1002/adma.201606380.
Abstract
Hydrogel optical fibers are utilized for continuous glucose sensing in real time. The hydrogel fibers consist of poly(acrylamide‐co‐poly(ethylene glycol) diacrylate) cores functionalized with phenylboronic acid. The complexation of the phenylboronic acid and cis‐diol groups of glucose enables reversible changes of the hydrogel fiber diameter. The analyses of light propagation loss allow for quantitative glucose measurements within the physiological range.
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Keywords
diagnostics, fiber optics, glucose sensing, hydrogels, light transmission
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