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Fine Particulate Exposure and Cardiac Autonomic Effects in Boilermakers
(2015-04-27)
Background: Heart Rate Variability (HRV) as a research outcome has the potential for misclassification due to its inability to account for changes in the heart rate. HRV can be parsed into Acceleration Capacity (AC) and ...
Health Effects of PM2.5 and Its Components on Mortality, Blood Pressure, and DNA Methylation
(2016-09-30)
Epidemiological studies have examined the association between PM2.5 mass and mortality, but there remains uncertainty about the relative importance of species. PM2.5 contains various species, such as organic carbon, elemental ...
Micrornas in Extracellular Vesicles as Novel Biomarkers in Environmental Epidemiology
(2016-05-03)
Despite important achievements of Environmental Epidemiology in identifying major environmental health problems in recent years, little is known about the underlying biological mechanisms that link environmental exposures ...
Maternal, Behavioral, and Environmental Risk Factors for Gestational Diabetes and Preterm Birth Among Pregnant Women
(2016-04-25)
Background: Lifestyle changed in Kuwait with the rapid development and economic expansion and the Americanization of the Kuwaiti market. Fast food and sedentary lifestyle became very prevalent. Environmental exposures such ...
Toward a Causal Health Effect of Fine Particulate Air Pollution
(2018-04-09)
Exposure to fine particulate matter (PM2.5) has been associated with many adverse health outcomes, including increased risk of mortality and hospital admissions. There have been criticisms challenging whether the reported ...
The Impacts of Environmental Exposures on Birthweight
(2018-04-19)
Environmental exposures have long been linked to health outcomes. This dissertation focuses on one outcome in particular, birthweight, as it is predictive of health status over the life course. The birth records of ...
Molecular Markers of Vitamin D and Esophageal Adenocarcinoma Prognosis
(2018-04-26)
Esophageal cancer is the ninth leading cause of cancer and the fifth leading cause of cancer death globally, with two predominant histologies: squamous cell carcinoma and adenocarcinoma. In the last few decades, esophageal ...
Prenatal Origins of Child Health: Independent and Joint Effects of Maternal Distress and Exposure to Air Pollution on Immune-Related Outcomes
(2018-04-27)
Objective: The aim of this dissertation was to examine, both independently and jointly, the association of prenatal exposure to maternal depression and air pollution with immune responses in the neonate at birth, and with ...
MODELING EXPOSURES to POLY- and PERFLUOROALKYL SUBSTANCES (PFASs) in AQUATIC BIOTA and HUMANS
(2018-04-27)
Poly- and perfluoroalkyl substances (PFASs) are a class of persistent anthropogenic chemicals widely used in consumer products. Exposure to PFASs has been associated with a suite of health effects including immunotoxicity, ...
A Global Perspective on Coal-Fired Power Plants, Climate Change and Disease Burden
(2018-04-27)
This dissertation investigates the disease burden from coal-fired power plants from global perspective. First, the study estimated changes in national lung cancer incidence decades after building or closing coal-fired power ...