Browsing DCE Theses and Dissertations by Author "Yang, Zinger"
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The Retromer Complex Protein VPS35 Modulates Iron Homeostasis by Regulating Hepcidin-Induced Ferroportin Degradation
Yang, Zinger (2018-02-28)Hepcidin-mediated degradation of the iron exporter Ferroportin is an essential mechanism for iron homeostasis. Upon Hepcidin binding to the Ferroportin receptor at the cell surface, Ferroportin is rapidly internalized and ...