Browsing Harvard Medical School by Title
Now showing items 3657-3676 of 18440
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Cost-effectiveness of Confirmatory Testing Before Treatment of Onychomycosis
(American Medical Association (AMA), 2016)Importance Onychomycosis is the most common disease of the nail in adults. International guidelines urge health care professionals to perform confirmatory diagnostic testing before initiating systemic therapy. This approach ... -
Cost-effectiveness of first-line antiretroviral therapy for HIV-infected African children less than 3 years of age
(Lippincott Williams & Wilkins, 2015)Background: The International Maternal, Pediatric, and Adolescent Clinical Trials P1060 trial demonstrated superior outcomes for HIV-infected children less than 3 years old initiating antiretroviral therapy (ART) with ... -
Cost-Effectiveness of Genotype Testing for Primary Resistance in Brazil
(JAIDS Journal of Acquired Immune Deficiency Syndromes, 2014)Objective: HIV genotype-resistance testing can help identify more effective antiretroviral treatment (ART) regimens for patients, substantially increasing the likelihood of viral suppression and immune recovery. We sought ... -
Cost-Effectiveness of HIV Testing Referral Strategies among Tuberculosis Patients in India
(Public Library of Science, 2010)Background: Indian guidelines recommend routine referral for HIV testing of all tuberculosis (TB) patients in the nine states with the highest HIV prevalence, and selective referral for testing elsewhere. We assessed the ... -
Cost-effectiveness of initiating extrafine- or standard size-particle inhaled corticosteroid for asthma in two health-care systems: a retrospective matched cohort study
(Nature Publishing Group, 2014)Background: Real-life studies are needed to determine the cost-effectiveness of asthma therapies in clinical practice. Aim: To compare the cost-effectiveness of extrafine-particle inhaled corticosteroid (ICS) with standard ... -
Cost-effectiveness of orbital atherectomy compared to rotational atherectomy in treating patients with severely calcified coronary artery lesions in Japan
(Springer Science and Business Media LLC, 2017-09-05)Compared to rotational atherectomy (RA), orbital atherectomy (OA) has been shown to decrease procedure failure and reintervention rates in the treatment of severely calcified coronary artery lesions. Our objective was to ... -
Cost-Effectiveness of Preventing Loss to Follow-up in HIV Treatment Programs: A Côte d'Ivoire Appraisal
(Public Library of Science, 2009)Background: Data from HIV treatment programs in resource-limited settings show extensive rates of loss to follow-up (LTFU) ranging from 5% to 40% within 6 mo of antiretroviral therapy (ART) initiation. Our objective was ... -
Cost-Effectiveness of Routine Screening for Autoimmune Encephalitis in Patients With First-Episode Psychosis in the United States
(Physicians Postgraduate Press, Inc, 2020-11-17) -
The Cost-Effectiveness of Surgical Fixation of Distal Radius Fractures: A Computer Model-Based Evaluation of Three Operative Modalities
(2018-05-15)Background: There is no consensus on the optimal fixation method for patients who require surgical management for distal radius fractures. We used a cost-effectiveness analysis to determine which of three modalities: closed ... -
Cost-Effectiveness of Tdap Vaccination of Adults Aged ≥65 Years in the Prevention of Pertussis in the US: A Dynamic Model of Disease Transmission
(Public Library of Science, 2014)Objectives: In February 2012, the Advisory Committee on Immunization Practices (ACIP) advised that all adults aged ≥65 years receive a single dose of reduced-antigen-content tetanus, diphtheria, and acellular pertussis ... -
Cost-Effectiveness of Treating Multidrug-Resistant Tuberculosis
(Public Library of Science, 2006)Background: Despite the existence of effective drug treatments, tuberculosis (TB) causes 2 million deaths annually worldwide. Effective treatment is complicated by multidrug-resistant TB (MDR TB) strains that respond only ... -
The Cost-Effectiveness of Tuberculosis Preventive Therapy for HIV-Infected Individuals in Southern India: A Trial-Based Analysis
(Public Library of Science, 2012)Background: Regimens for isoniazid-based preventive therapy (IPT) for tuberculosis (TB) in HIV-infected individuals have not been widely adopted given concerns regarding efficacy, adherence and drug resistance. Further, ... -
Cost-Effectiveness of World Health Organization 2010 Guidelines for Prevention of Mother-to-Child HIV Transmission in Zimbabwe
(Oxford University Press, 2012)Background. In 2010, the World Health Organization (WHO) released revised guidelines for prevention of mother-to-child human immunodeficiency virus (HIV) transmission (PMTCT). We projected clinical impacts, costs, and ... -
Cost-Minimization Analysis of Computed Tomography versus Magnetic Resonance Imaging in the Evaluation of Patients with Transient Ischemic Attacks at a Large Academic Center
(S. Karger AG, 2014)Background: The type of neuroimaging for the evaluation of transient ischemic attack (TIA) is debatable. Many patients undergo head computed tomography (CT) with or without CT angiogram (CTA) while being at the emergency ... -
Cost-minimization analysis of three decision strategies for cardiac revascularization: results of the “suspected CAD” cohort of the european cardiovascular magnetic resonance registry
(BioMed Central, 2016)Background: Coronary artery disease (CAD) continues to be one of the top public health burden. Perfusion cardiovascular magnetic resonance (CMR) is generally accepted to detect CAD, while data on its cost effectiveness are ... -
Cost-Related Medication Nonadherence After Implementation of Medicare Part D, 2006-2007
(American Medical Association, 2009)To the Editor: High drug costs cause some elderly or disabled patients to take less medication than prescribed or forgo basic needs to pay for medicines. The 2006 Medicare Part D drug benefit was intended to increase ... -
Cost-Related Medication Nonadherence Among Elderly and Disabled Medicare Beneficiaries
(American Medical Association (AMA), 2006)Background Prior to implementation of the Medicare drug benefit, we estimated the prevalence of cost-related medication nonadherence (CRN) among Medicare enrollees, including elderly and nonelderly disabled beneficiarie ... -
Cost-Related Medication Nonadherence and Spending on Basic Needs Following Implementation of Medicare Part D
(American Medical Association (AMA), 2008)Context Cost-related medication nonadherence (CRN) has been a persistent problem for individuals who are elderly and disabled in the United States. The impact of Medicare prescription drug coverage (Part D) on CRN is ... -
Costs and Consequences Associated With Misdiagnosed Lower Extremity Cellulitis
(American Medical Association (AMA), 2017)Question What is the national health care burden of misdiagnosed lower extremity cellulitis in patients admitted to the hospital from the emergency department? Findings In this cross-sectional study that included 259 ... -
Costs and Consequences of Direct-to-Consumer Advertising for Clopidogrel in Medicaid
(American Medical Association (AMA), 2009)Background Direct-to-consumer advertising (DTCA) is assumed to be a major driver of rising pharmaceutical costs. Yet, research on how it affects costs is limited. Therefore, we studied clopidogrel, a commonly used and ...