Browsing Harvard Medical School by Title
Now showing items 451-470 of 18448
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Adrenergic receptor genotype influences heart failure severity and β-blocker response in children with dilated cardiomyopathy
(Nature Publishing Group, 2015)Background: Adrenergic receptor (ADR) genotypes are associated with heart failure (HF) and β-blocker response in adults. We assessed the influence of ADR genotypes in children with dilated cardiomyopathy (DCM). Methods: ... -
Adult axolotls can regenerate original neuronal diversity in response to brain injury
(eLife Sciences Publications, Ltd, 2016)The axolotl can regenerate multiple organs, including the brain. It remains, however, unclear whether neuronal diversity, intricate tissue architecture, and axonal connectivity can be regenerated; yet, this is critical for ... -
Adult Behavior in Male Mice Exposed to E-Cigarette Nicotine Vapors during Late Prenatal and Early Postnatal Life
(Public Library of Science, 2015)Nicotine exposure has been associated with an increased likelihood of developing attention deficit hyperactivity disorder (ADHD) in offspring of mothers who smoked during pregnancy. The goal of this study was to determine ... -
Adult Cardiac Progenitor Cell Aggregates Exhibit Survival Benefit Both In Vitro and In Vivo
(Public Library of Science, 2012)Background: A major hurdle in the use of exogenous stems cells for therapeutic regeneration of injured myocardium remains the poor survival of implanted cells. To date, the delivery of stem cells into myocardium has largely ... -
Adult hippocampal neurogenesis and pattern separation in DG: a role for feedback inhibition in modulating sparseness to govern population-based coding
(Frontiers Media S.A., 2015)The dentate gyrus (DG) of mammals harbors neural stem cells that generate new dentate granule cells (DGCs) throughout life. Behavioral studies using the contextual fear discrimination paradigm have found that selectively ... -
Adult neurogenesis and the olfactory system
(Elsevier BV, 2009)Though initially described in the early 1960s, it is only within the past decade that the concept of continuing adult neurogenesis has gained widespread acceptance. Neuroblasts from the subventricular zone (SVZ) migrate ... -
Adult neurogenesis modifies excitability of the dentate gyrus
(Frontiers Media S.A., 2013)Adult-born dentate granule neurons contribute to memory encoding functions of the dentate gyrus (DG) such as pattern separation. However, local circuit-mechanisms by which adult-born neurons partake in this process are ... -
Adult Onset Leukodystrophy with Neuroaxonal Spheroids: Clinical, Neuroimaging and Neuropathologic Observations
(Wiley-Blackwell, 2009)Pigmented orthochromatic leukodystrophy (POLD) and Hereditary diffuse leukoencephalopathy with spheroids HDLS are two adult onset leukodystrophies with neuroaxonal spheroids presenting with prominent neurobehavioral, ... -
Adult-Oriented Health Insurance Reform and Children's Health Insurance: the Massachusetts Experience and Implications for the Affordable Care Act
(2016-05-17)BACKGROUND: The Massachusetts health reform and the Affordable Care Act (ACA) were focused on adults, but have the potential to reduce uninsurance and increase access to affordable health care for children. Little is known ... -
Adulterated Sexual Enhancement Supplements
(American Medical Association (AMA), 2013-07-08) -
The ADVANCE network: accelerating data value across a national community health center network
(BMJ Publishing Group, 2014)The ADVANCE (Accelerating Data Value Across a National Community Health Center Network) clinical data research network (CDRN) is led by the OCHIN Community Health Information Network in partnership with Health Choice Network ... -
Advanced Breast Imaging Availability by Screening Facility Characteristics
(Elsevier BV, 2015)RATIONALE AND OBJECTIVES: To determine the relationship between screening mammography facility characteristics and on-site availability of advanced breast imaging services required for supplemental screening and the ... -
Advanced Motion Compensation Methods for Intravital Optical Microscopy
(Institute of Electrical and Electronics Engineers, 2014)Intravital microscopy has emerged in the recent decade as an indispensible imaging modality for the study of the microdynamics of biological processes in live animals. Technical advancements in imaging techniques and ... -
Advanced nodal stage predicts venous thromboembolism in patients with locally advanced non-small cell lung cancer
(Elsevier BV, 2016)Objectives: Patients with non-small cell lung cancer (NSCLC) are known to be at high risk for venous thromboembolism (VTE), but previous studies have not specifically analyzed locally advanced disease. We performed a ... -
Advanced Signal Processing Methods for Biomedical Imaging
(Hindawi Publishing Corporation, 2013) -
Advances in complex multiparameter flow cytometry technology: Applications in stem cell research
(Wiley-Blackwell, 2009)Flow cytometry and cell sorting are critical tools in stem cell research. Recent advances in flow cytometric hardware, reagents, and software have synergized to permit the stem cell biologist to more full identify and ... -
Advances in Estrogen Receptor Biology: Prospects for Improvements in Targeted Breast Cancer Therapy
(BioMed Central, 2003)Estrogen receptor (ER) has a crucial role in normal breast development and is expressed in the most common breast cancer subtypes. Importantly, its expression is very highly predictive for response to endocrine therapy. ... -
Advances in Multidetector CT Diagnosis of Pediatric Pulmonary Thromboembolism
(The Korean Society of Radiology, 2016)Although pediatric pulmonary thromboembolism is historically believed to be rare with relatively little information available in the medical literature regarding its imaging evaluation, it is more common than previously ... -
Advances in the Science, Treatment, and Prevention of the Disease of Obesity: Reflections From a Diabetes Care Editors’ Expert Forum
(American Diabetes Association, 2015)As obesity rates increase, so too do the risks of type 2 diabetes, cardiovascular disease, and numerous other detrimental conditions. The prevalence of obesity in U.S. adults more than doubled between 1980 and 2010, from ...