Browsing Harvard Medical School by Keyword "histone modification"
Now showing items 1-3 of 3
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GC-rich sequence elements recruit PRC2 in mammalian ES cells
(Public Library of Science, 2010)Polycomb proteins are epigenetic regulators that localize to developmental loci in the early embryo where they mediate lineage-specific gene repression. In Drosophila, these repressors are recruited to sequence elements ... -
Ornithine Decarboxylase Antizyme Induces Hypomethylation of Genome DNA and Histone H3 Lysine 9 Dimethylation (H3K9me2) in Human Oral Cancer Cell Line
(Public Library of Science, 2010)Background: Methylation of CpG islands of genome DNA and lysine residues of histone H3 and H4 tails regulates gene transcription. Inhibition of polyamine synthesis by ornithine decarboxylase antizyme-1 (OAZ) in human oral ... -
XY and ZW: Is Meiotic Sex Chromosome Inactivation the Rule in Evolution?
(Public Library of Science, 2009)