Browsing Harvard Medical School by Keyword "infection"
Now showing items 1-12 of 12
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Antimicrobial Proteins and Peptides in Early Life: Ontogeny and Translational Opportunities
(Frontiers Media S.A., 2016)While developing adaptive immune responses, young infants are especially vulnerable to serious infections, including sepsis, meningitis, and pneumonia. Antimicrobial proteins and peptides (APPs) are key effectors that ... -
Bacterial endophthalmitis: Therapeutic challenges and host–pathogen interactions
(Elsevier BV, 2007)Endophthalmitis is an infection of the posterior segment of the eye that frequently results in loss of vision. This devastating result occurs despite prompt and often aggressive therapeutic and surgical intervention. Over ... -
Childhood infections and asthma: at the crossroads of the hygiene and Barker hypotheses
(BioMed Central, 2001)The hygiene hypothesis states that childhood asthma develops as a result of decreased exposure to infectious agents during infancy and early childhood. This results in the persistence of the neonatal T helper lymphocyte 2 ... -
Colonization with Antibiotic-Susceptible Strains Protects against Methicillin-Resistant Staphylococcus aureus but not Vancomycin-Resistant Enterococci Acquisition: A Nested Case-Control Study
(BioMed Central, 2011)Introduction: Harboring sensitive strains may prevent acquisition of resistant pathogens by competing for colonization of ecological niches. Competition may be relevant to decolonization strategies that eliminate sensitive ... -
The Extended Family of CD1d-Restricted NKT Cells: Sifting through a Mixed Bag of TCRs, Antigens, and Functions
(Frontiers Media S.A., 2015)Natural killer T (NKT) cells comprise a family of specialized T cells that recognize lipid antigens presented by CD1d. Based on their T cell receptor (TCR) usage and antigen specificities, CD1d-restricted NKT cells have ... -
Honey’s Ability to Counter Bacterial Infections Arises from Both Bactericidal Compounds and QS Inhibition
(Frontiers Research Foundation, 2012)The ability of honey to kill bacterial pathogens in vitro and quickly clear even chronic or drug-resistant infections has been demonstrated by several studies. Most current research is focused on identifying the bactericidal ... -
Imported Fasciola hepatica Infection in the United States and Treatment with Triclabendazole
(Oxford University Press (OUP), 2001)Infection with Fasciola hepatica, a liver trematode, is not frequently reported in the United States. We describe 2 patients, both originally from Cape Verde, who illustrate the spectrum of clinical presentations of F. ... -
Influence of Bioaerosol Source Location and Ceiling Fan Direction on Eggcrate Upper-room Ultraviolet Germicidal Irradiation
(2015)Background: Eggcrate upper-room ultraviolet germicidal irradiation (UVGI), an engineering control method for reducing the airborne transmission of infectious diseases, was recently developed as an alternative to conventional ... -
Omental Cakes: Unusual Aetiologies and CT Appearances
(Springer-Verlag, 2011)Background: Omental cakes typically are associated with ovarian carcinoma, as this is the most common malignant aetiology. Nonetheless, numerous other neoplasms, as well as infectious and benign processes, can produce ... -
Pediatric sepsis: Important considerations for diagnosing and managing severe infections in infants, children, and adolescents
(Landes Bioscience, 2014)Sepsis is the leading cause of death in children worldwide. Although the diagnosis and management of sepsis in infants and children is largely influenced by studies done in adults, there are important considerations relevant ... -
TNF-α/IL-10 Ratio Correlates with Burn Severity and May Serve as a Risk Predictor of Increased Susceptibility to Infections
(Frontiers Media S.A., 2016)Severe burn injury renders patients susceptible to multiple infection episodes; however, identifying specific patient groups at high risk remains challenging. Burn-induced inflammatory response dramatically modifies the ... -
Vitamin D Status and Acute Respiratory Infection: Cross Sectional Results from the United States National Health and Nutrition Examination Survey, 2001–2006
(MDPI, 2015)Vitamin D is a promising, though under-explored, potential modifiable risk factor for acute respiratory infections (ARIs). We sought to investigate the association of vitamin D status with ARI in a large, nationally-representative ...