Browsing HMS Scholarly Articles by Author "Cao, Luxiang"

Now showing items 1-2 of 2

    • \(A\beta\) alters the connectivity of olfactory neurons in the absence of amyloid plaques in vivo 

      Cao, Luxiang; Schrank, Benjamin R.; Rodriguez, Steven; Benz, Eric G.; Moulia, Thomas W.; Rickenbacher, Gregory T.; Gomez, Alexis C.; Levites, Yona; Edwards, Sarah R.; Golde, Todd E.; Hyman, Bradley Theodore; Barnea, Gilad; Albers, Mark W (Nature Publishing Group, 2012)
      The amyloid beta peptide aggregates into amyloid plaques at presymptomatic stages of Alzheimer's disease, but the temporal relationship between plaque formation and neuronal dysfunction is poorly understood. Here we ...

    • The Precision of Axon Targeting of Mouse Olfactory Sensory Neurons Requires the BACE1 Protease 

      Cao, Luxiang; Rickenbacher, Gregory T.; Rodriguez, Steven; Moulia, Thomas W.; Albers, Mark W. (Nature Publishing Group, 2012)
      The \(\beta\)-site amyloid precursor protein cleaving enzyme 1 (BACE1) is necessary to generate the A\(\beta\) peptide, which is implicated in Alzheimer's disease pathology. Studies show that the expression of BACE1 and ...