Browsing HMS Scholarly Articles by Title

Now showing items 9870-9889 of 17922

    • Low dose compared to variable dose Warfarin and to Fondaparinux as prophylaxis for thromboembolism after elective hip or knee replacement surgery; a randomized, prospective study 

      Bern, Murray M.; Hazel, Diane; Deeran, Elizabeth; Richmond, John R.; Ward, Daniel M.; Spitz, Damon J.; Mattingly, David A.; Bono, James V.; Berezin, Ronna H.; Hou, Laura; Miley, Gerald B.; Bierbaum, Benjamin E. (BioMed Central, 2015)
      Background: Deep vein thrombosis (DVT) and pulmonary emboli (PE), known together as venous thromboembolic (VTE) disease remain major complications following elective hip and knee surgery. This study compares three ...

    • Low Incidence of Chest Wall Pain with a Risk-Adapted Lung Stereotactic Body Radiation Therapy Approach Using Three or Five Fractions Based on Chest Wall Dosimetry 

      Coroller, Thibaud P.; Mak, Raymond H.; Lewis, John H.; Baldini, Elizabeth H.; Chen, Aileen B.; Colson, Yolonda L.; Hacker, Fred L.; Hermann, Gretchen; Kozono, David; Mannarino, Edward; Molodowitch, Christina; Wee, Jon O.; Sher, David J.; Killoran, Joseph H. (Public Library of Science, 2014)
      Purpose To examine the frequency and potential of dose-volume predictors for chest wall (CW) toxicity (pain and/or rib fracture) for patients receiving lung stereotactic body radiotherapy (SBRT) using treatment planning ...

    • Low LDL-C and High HDL-C Levels Are Associated with Elevated Serum Transaminases amongst Adults in the United States: A Cross-sectional Study 

      Jiang, Zhenghui Gordon; Mukamal, Kenneth; Tapper, Elliot; Robson, Simon C.; Tsugawa, Yusuke (Public Library of Science, 2014)
      Background: Dyslipidemia, typically recognized as high serum triglyceride, high low-density lipoprotein cholesterol (LDL-C) or low high-density lipoprotein cholesterol (HDL-C) levels, are associated with nonalcoholic fatty ...

    • Low Levels of Peripheral CD161++CD8+ Mucosal Associated Invariant T (MAIT) Cells Are Found in HIV and HIV/TB Co-Infection 

      Wong, Emily B.; Akilimali, Ngomu Akeem; Govender, Pamla; Sullivan, Zuri A.; Cosgrove, Cormac; Pillay, Mona; Lewinsohn, David M.; Bishai, William R.; Walker, Bruce D.; Ndung'u, Thumbi; Klenerman, Paul; Kasprowicz, Victoria O. (Public Library of Science, 2013)
      Background: High expression of CD161 on CD8+ T cells is associated with a population of cells thought to play a role in mucosal immunity. We wished to investigate this subset in an HIV and Mycobacterium tuberculosis (MTB) ...

    • Low Nephron Number and Its Clinical Consequences 

      Luyckx, Valerie A.; Shukha, Khuloud; Brenner, Barry M. (Rambam Health Care Campus, 2011)
      Epidemiologic studies now strongly support the hypothesis, proposed over two decades ago, that developmental programming of the kidney impacts an individual’s risk for hypertension and renal disease in later life. Low birth ...

    • Low prevalence of myocilin mutations in an African American population with primary open-angle glaucoma 

      Liu, Yutao; Challa, Pratap; Herndon, Leon W.; Girkin, Christopher A.; Allingham, R. Rand; Hauser, Michael A.; Liu, Wenjing; Wiggs, Janey Lee (Molecular Vision, 2012)
      Purpose Mutations in the myocilin gene (MYOC) are associated with primary open-angle glaucoma (POAG) in many different populations. This study represents the first large survey of MYOC mutations in an African American ...

    • Low Resistance to First and Second Line Anti-Tuberculosis Drugs among Treatment Naive Pulmonary Tuberculosis Patients in Southwestern Uganda 

      Orikiriza, Patrick; Tibenderana, Becky; Siedner, Mark J.; Mueller, Yolanda; Byarugaba, Frederick; Moore, Christopher C.; Evans, Emily E.; Bonnet, Maryline; Page, Anne-Laure; Bazira, Joel; Boum II, Yap (Public Library of Science, 2015)
      Background: There are limited data on region-specific drug susceptibility of tuberculosis (TB) in Uganda. We performed resistance testing on specimens collected from treatment-naive patients with pulmonary TB in Southwestern ...

    • Low respiratory sinus arrhythmia and prolonged psychophysiological arousal in posttraumatic stress disorder: heart rate dynamics and individual differences in arousal regulation 

      Sack, Martin; Hopper, James W.; Lamprecht, Friedhelm (Elsevier BV, 2004)
      Background: There is extensive evidence that the parasympathetic branch of the autonomic nervous system can modulate psychophysiological arousal. To date, no studies have investigated associations between cardiac vagal ...

    • Low Serum 25-Hydroxyvitamin D Levels and Acute Kidney Injury in the Critically Ill 

      Braun, AB; Litonjua, AA; Moromizato, Takuhiro; Gibbons, FK; Giovannucci, Edward L.; Christopher, KB (BioMed Central, 2012)

    • Low Usefulness of Potassium Monitoring Among Healthy Young Women Taking Spironolactone for Acne 

      Plovanich, Molly Elizabeth; Weng, Qing Yu; Mostaghimi, Arash (American Medical Association (AMA), 2015)
      Importance Spironolactone has been shown to be an effective treatment option for hormonally mediated acne but can cause hyperkalemia. The prevalence of hyperkalemia among healthy young women taking spironolactone for acne ...

    • Low Utilization of Obesity Medications: What are the Implications for Clinical Care? 

      Kyle, Theodore K.; Stanford, Fatima (Wiley-Blackwell, 2016)
      In a new analysis of dispensed prescriptions for obesity medications, Thomas et al. (1) quantify the extent of a problem that until now has only been described qualitatively. Prescribing of obesity medications, and especially ...

    • Low-Concentration PM2.5 and Mortality: Estimating Acute and Chronic Effects in a Population-Based Study 

      Shi, Liuhua; Zanobetti, Antonella; Kloog, Itai; Coull, Brent A.; Koutrakis, Petros; Melly, Steven J.; Schwartz, Joel D. (National Institute of Environmental Health Sciences, 2015)
      Background: Both short- and long-term exposures to fine particulate matter (≤ 2.5 μm; PM2.5) are associated with mortality. However, whether the associations exist at levels below the new U.S. Environmental Protection ...

    • Low-Cost and Readily Available Tissue Carriers for the Boston Keratoprosthesis: A Review of Possibilities 

      Cruzat, Andrea; Tauber, Allyson; Shukla, Anita; Paschalis, Eleftherios I.; Pineda, Roberto; Dohlman, Claes H. (Hindawi Publishing Corporation, 2013)
      The Boston keratoprosthesis (B-KPro), currently the most commonly used artificial cornea worldwide, can provide rapid visual rehabilitation for eyes with severe corneal opacities not suitable for standard corneal ...

    • Low-Cost High-Performance MRI 

      Sarracanie, Mathieu; LaPierre, Cristen D.; Salameh, Najat; Waddington, David E. J.; Witzel, Thomas; Rosen, Matthew S. (Nature Publishing Group, 2015)
      Magnetic Resonance Imaging (MRI) is unparalleled in its ability to visualize anatomical structure and function non-invasively with high spatial and temporal resolution. Yet to overcome the low sensitivity inherent in ...

    • Low-Density Lipoproteins Containing Apolipoprotein C-III and the Risk of Coronary Heart Disease 

      Mendivil, C. O.; Rimm, Eric Bruce; Furtado, Jeremy Daniel; Chiuve, Stephanie Elizabeth; Sacks, Frank Martin (Ovid Technologies (Wolters Kluwer Health), 2011)
      BACKGROUND: Low-density lipoprotein (LDL) that contains apolipoprotein (apo) C-III makes up only 10% to 20% of plasma LDL but has a markedly altered metabolism and proatherogenic effects on vascular cells. METHODS AND ...

    • Low-dose Propofol–induced Amnesia Is Not due to a Failure of Encoding 

      Veselis, Robert A.; Pryor, Kane O.; Reinsel, Ruth A.; Mehta, Meghana; Pan, Hong; Johnson, Ray (Ovid Technologies (Wolters Kluwer Health), 2008)
      Background—Propofol may produce amnesia by affecting encoding. The hypothesis that propofol weakens encoding was tested by measuring regional cerebral blood flow during verbal encoding. Methods—17 volunteer participants ...

    • Low-Dose Rectal Inoculation of Rhesus Macaques by SIVsmE660 or SIVmac251 Recapitulates Human Mucosal Infection by HIV-1 

      Keele, Brandon F.; Learn, Gerald H.; Hraber, Peter; Giorgi, Elena E.; Grayson, Truman; Sun, Chuanxi; Chen, Yalu; Mascola, John R.; Nabel, Gary J.; Haynes, Barton F.; Bhattacharya, Tanmoy; Perelson, Alan S.; Korber, Bette T.; Hahn, Beatrice H.; Shaw, George M.; Li, Hui; Yeh, Wendy Wen-Li; Letvin, Norman Lee (Rockefeller University Press, 2009)
      We recently developed a novel strategy to identify transmitted HIV-1 genomes in acutely infected humans using single-genome amplification and a model of random virus evolution. Here, we used this approach to determine the ...

    • Low-dose ultraviolet-B irradiation of donor corneal endothelium and graft survival 

      Dana, Reza; Olkowski, Steven; Ahmadian, Houshang; Stark, Walter J.; Young, Elaine M. (Association for Research in Vision and Ophthalmology, 1990)
      Donor rabbit corneal endothelium was pretreated with different doses of ultraviolet (UV-B) irradiation (302 nm) before grafting to test whether allograft survival could be favorably affected in comparison with untreated ...

    • Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility 

      Wessel, Jennifer; Chu, Audrey Y; Willems, Sara M; Wang, Shuai; Yaghootkar, Hanieh; Brody, Jennifer A; Dauriz, Marco; Hivert, Marie-France; Raghavan, Sridharan; Lipovich, Leonard; Hidalgo, Bertha; Fox, Keolu; Huffman, Jennifer E; An, Ping; Lu, Yingchang; Rasmussen-Torvik, Laura J; Grarup, Niels; Ehm, Margaret G; Li, Li; Baldridge, Abigail S; Stančáková, Alena; Abrol, Ravinder; Besse, Céline; Boland, Anne; Bork-Jensen, Jette; Fornage, Myriam; Freitag, Daniel F; Garcia, Melissa E; Guo, Xiuqing; Hara, Kazuo; Isaacs, Aaron; Jakobsdottir, Johanna; Lange, Leslie A; Layton, Jill C; Li, Man; Hua Zhao, Jing; Meidtner, Karina; Morrison, Alanna C; Nalls, Mike A; Peters, Marjolein J; Sabater-Lleal, Maria; Schurmann, Claudia; Silveira, Angela; Smith, Albert V; Southam, Lorraine; Stoiber, Marcus H; Strawbridge, Rona J; Taylor, Kent D; Varga, Tibor V; Allin, Kristine H; Amin, Najaf; Aponte, Jennifer L; Aung, Tin; Barbieri, Caterina; Bihlmeyer, Nathan A; Boehnke, Michael; Bombieri, Cristina; Bowden, Donald W; Burns, Sean M; Chen, Yuning; Chen, Yii-DerI; Cheng, Ching-Yu; Correa, Adolfo; Czajkowski, Jacek; Dehghan, Abbas; Ehret, Georg B; Eiriksdottir, Gudny; Escher, Stefan A; Farmaki, Aliki-Eleni; Frånberg, Mattias; Gambaro, Giovanni; Giulianini, Franco; Goddard, William A; Goel, Anuj; Gottesman, Omri; Grove, Megan L; Gustafsson, Stefan; Hai, Yang; Hallmans, Göran; Heo, Jiyoung; Hoffmann, Per; Ikram, Mohammad K; Jensen, Richard A; Jørgensen, Marit E; Jørgensen, Torben; Karaleftheri, Maria; Khor, Chiea C; Kirkpatrick, Andrea; Kraja, Aldi T; Kuusisto, Johanna; Lange, Ethan M; Lee, I T; Lee, Wen-Jane; Leong, Aaron; Liao, Jiemin; Liu, Chunyu; Liu, Yongmei; Lindgren, Cecilia M; Linneberg, Allan; Malerba, Giovanni; Mamakou, Vasiliki; Marouli, Eirini; Maruthur, Nisa M; Matchan, Angela; McKean-Cowdin, Roberta; McLeod, Olga; Metcalf, Ginger A; Mohlke, Karen L; Muzny, Donna M; Ntalla, Ioanna; Palmer, Nicholette D; Pasko, Dorota; Peter, Andreas; Rayner, Nigel W; Renström, Frida; Rice, Ken; Sala, Cinzia F; Sennblad, Bengt; Serafetinidis, Ioannis; Smith, Jennifer A; Soranzo, Nicole; Speliotes, Elizabeth K; Stahl, Eli A; Stirrups, Kathleen; Tentolouris, Nikos; Thanopoulou, Anastasia; Torres, Mina; Traglia, Michela; Tsafantakis, Emmanouil; Javad, Sundas; Yanek, Lisa R; Zengini, Eleni; Becker, Diane M; Bis, Joshua C; Brown, James B; Adrienne Cupples, L; Hansen, Torben; Ingelsson, Erik; Karter, Andrew J; Lorenzo, Carlos; Mathias, Rasika A; Norris, Jill M; Peloso, Gina M; Sheu, Wayne H.-H.; Toniolo, Daniela; Vaidya, Dhananjay; Varma, Rohit; Wagenknecht, Lynne E; Boeing, Heiner; Bottinger, Erwin P; Dedoussis, George; Deloukas, Panos; Ferrannini, Ele; Franco, Oscar H; Franks, Paul W; Gibbs, Richard A; Gudnason, Vilmundur; Hamsten, Anders; Harris, Tamara B; Hattersley, Andrew T; Hayward, Caroline; Hofman, Albert; Jansson, Jan-Håkan; Langenberg, Claudia; Launer, Lenore J; Levy, Daniel; Oostra, Ben A; O'Donnell, Christopher J; O'Rahilly, Stephen; Padmanabhan, Sandosh; Pankow, James S; Polasek, Ozren; Province, Michael A; Rich, Stephen S; Ridker, Paul M; Rudan, Igor; Schulze, Matthias B; Smith, Blair H; Uitterlinden, André G; Walker, Mark; Watkins, Hugh; Wong, Tien Y; Zeggini, Eleftheria; Sharp, Stephen J; Forouhi, Nita G; Kerrison, Nicola D; Lucarelli, Debora ME; Sims, Matt; Barroso, Inês; McCarthy, Mark I; Arriola, Larraitz; Balkau, Beverley; Barricarte, Aurelio; Gonzalez, Carlos; Grioni, Sara; Kaaks, Rudolf; Key, Timothy J; Navarro, Carmen; Nilsson, Peter M; Overvad, Kim; Palli, Domenico; Panico, Salvatore; Quirós, J. Ramón; Rolandsson, Olov; Sacerdote, Carlotta; Sánchez, María–José; Slimani, Nadia; Tjonneland, Anne; Tumino, Rosario; van der A, Daphne L; van der Schouw, Yvonne T; Riboli, Elio; Laakso, Markku; Borecki, Ingrid B; Chasman, Daniel I; Pedersen, Oluf; Psaty, Bruce M; Shyong Tai, E; van Duijn, Cornelia M; Wareham, Nicholas J; Waterworth, Dawn M; Boerwinkle, Eric; Linda Kao, W H; Florez, Jose C; Loos, Ruth J.F.; Wilson, James G; Frayling, Timothy M; Siscovick, David S; Dupuis, Josée; Rotter, Jerome I; Meigs, James B; Scott, Robert A; Goodarzi, Mark O (Nature Pub. Group, 2015)
      Fasting glucose and insulin are intermediate traits for type 2 diabetes. Here we explore the role of coding variation on these traits by analysis of variants on the HumanExome BeadChip in 60,564 non-diabetic individuals ...

    • Low-level Environmental Lead Exposure and Children’s Intellectual Function: An International Pooled Analysis 

      Lanphear, Bruce P.; Hornung, Richard; Khoury, Jane; Yolton, Kimberly; Baghurst, Peter; Canfield, Richard L.; Dietrich, Kim N.; Bornschein, Robert; Greene, Tom; Needleman, Herbert L.; Schnaas, Lourdes; Wasserman, Gail; Graziano, Joseph; Roberts, Russell; Bellinger, David C.; Rothenberg, Stephen J. (National Institue of Environmental Health Sciences, 2005)
      Lead is a confirmed neurotoxin, but questions remain about lead-associated intellectual deficits at blood lead levels < 10 μg/dL and whether lower exposures are, for a given change in exposure, associated with greater ...