Browsing Faculty of Arts and Sciences by Author "Flavell, Richard A."

Now showing items 1-2 of 2

    • The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan 

      Kotzin, Jonathan J.; Spencer, Sean Paul; McCright, Sam J.; Kumar, Dinesh B. Uthaya; Collet, Magalie A.; Mowel, Walter K.; Elliott, Ellen N.; Uyar, Asli; Makiya, Michelle A.; Dunagin, Margaret C.; Harman, Christian C.D.; Virtue, Anthony T.; Zhu, Stella; Bailis, Will; Stein, Judith; Hughes, Cynthia; Raj, Arjun; Wherry, E. John; Goff, Loyal; Klion, Amy D.; Rinn, John L; Williams, Adam; Flavell, Richard A.; Henao-Mejia, Jorge (Springer Nature, 2016)
      Neutrophils, eosinophils and “classical” monocytes collectively account for ~70% ofhuman blood leukocytes and are among the shortest-lived cells in the body. Precise regulation of the lifespan of these myeloid cells is ...

    • Skin-resident innate lymphoid cells converge on a pathogenic effector state 

      Bielecki, Piotr; Riesenfeld, Samantha J.; Hütter, Jan-Christian; Torlai Triglia, Elena; Kowalczyk, Monika S.; Ricardo-Gonzalez, Roberto R.; Lian, Mi; Amezcua Vesely, Maria C.; Kroehling, Lina; Xu, Hao; Slyper, Michal; Muus, Christoph; Ludwig, Leif S.; Christian, Elena; Tao, Liming; Kedaigle, Amanda J.; Steach, Holly R.; York, Autumn G.; Skadow, Mathias H.; Yaghoubi, Parastou; Dionne, Danielle; Jarret, Abigail; McGee, Heather M.; Porter, Caroline B. M.; Licona-Limón, Paula; Bailis, Will; Jackson, Ruaidhrí; Gagliani, Nicola; Gasteiger, Georg; Locksley, Richard M.; Regev, Aviv; Flavell, Richard A. (Springer Science and Business Media LLC, 2021-02-03)
      Tissue-resident innate lymphoid cells (ILCs) help sustain barrier function and respond to local signals. ILCs are traditionally divided into subsets (ILC1/ILC2/ILC3) based on transcription factors (TFs) and cytokines1. In ...