Browsing Faculty of Arts and Sciences by Author "Chen, Shiming"
Now showing items 1-1 of 1
-
Graded gene expression changes determine phenotype severity in mouse models of CRX-associated retinopathies
Ruzycki, Philip A.; Tran, Nicholas M.; Kefalov, Vladimir J.; Kolesnikov, Alexander V.; Chen, Shiming (BioMed Central, 2015)Background: Mutations in the cone-rod-homeobox protein CRX are typically associated with dominant blinding retinopathies with variable age of onset and severity. Five well-characterized mouse models carrying different Crx ...