Browsing Faculty of Arts and Sciences by Author "Reed, John C."
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A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity
Qiao, Shuxi; Dennis, Michael; Song, Xiufeng; Vadysirisack, Douangsone D.; Salunke, Devika; Nash, Zachary; Yang, Zhifen; Liesa, Marc; Yoshioka, Jun; Matsuzawa, Shu-Ichi; Shirihai, Orian S.; Lee, Richard T.; Reed, John C.; Ellisen, Leif W. (Nature Pub. Group, 2015)Macroautophagy (autophagy) is a critical cellular stress response; however, the signal transduction pathways controlling autophagy induction in response to stress are poorly understood. Here we reveal a new mechanism of ...