Browsing Faculty of Arts and Sciences by Author "Ebert, Benjamin L"
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Discovery of Novel Molecular Glues and Targeted Protein Degradation Mechanisms for Cancer Therapeutics
Li, Yen-Der (2023-05-03)Targeted protein degradation has emerged as a promising therapeutic approach that recruits cellular degradation machineries to induce degradation of target proteins. However, the mechanisms underlying many small molecule ... -
Genetic Determinants and Evolutionary Trajectories of Chronic Lymphocytic Leukemia
Gutierrez, Catherine (2020-11-23)Chronic lymphocytic leukemia (CLL), the most common adult B cell malignancy, is known to have a variable disease course and multiple modes of therapeutic resistance. Recent large-scale sequencing efforts have uncovered ...