Now showing items 1-1 of 1

    • Unraveling the clonal hierarchy of somatic genomic aberrations 

      Prandi, Davide; Baca, Sylvan C; Romanel, Alessandro; Barbieri, Christopher E; Mosquera, Juan-Miguel; Fontugne, Jacqueline; Beltran, Himisha; Sboner, Andrea; Garraway, Levi A; Rubin, Mark A; Demichelis, Francesca (BioMed Central, 2014)
      Defining the chronology of molecular alterations may identify milestones in carcinogenesis. To unravel the temporal evolution of aberrations from clinical tumors, we developed CLONET, which upon estimation of tumor admixture ...