Now showing items 1-8 of 8

    • Angiotensin II Induced Cardiac Dysfunction on a Chip 

      Horton, Renita E.; Yadid, Moran; McCain, Megan L.; Sheehy, Sean P.; Pasqualini, Francesco S.; Park, Sung-Jin; Cho, Alexander; Campbell, Patrick; Parker, Kevin Kit (Public Library of Science, 2016)
      In vitro disease models offer the ability to study specific systemic features in isolation to better understand underlying mechanisms that lead to dysfunction. Here, we present a cardiac dysfunction model using angiotensin ...
    • Computing Complex Visual Features with Retinal Spike Times 

      Gütig, Robert; Gollisch, Tim; Sompolinsky, Haim I; Meister, Markus (Public Library of Science, 2013)
      Neurons in sensory systems can represent information not only by their firing rate, but also by the precise timing of individual spikes. For example, certain retinal ganglion cells, first identified in the salamander, ...
    • Connectivity and computations in higher-order olfactory neurons in Drosophila 

      Fisek, Mehmet (2014-06-06)
      Understanding how odors are encoded in the brain is of fundamental importance to neurobiology. The first two stages of olfactory information processing have been relatively well studied in both vertebrates and invertebrates. ...
    • Diverse physiology and function of dopaminergic neurons in behaving Drosophila 

      Marquis, Michael Julian (2021-05-14)
      In many animals, including both mammals and insects like Drosophila, dopamine is associated with learning, motivation, and regulation of voluntary movement. In mammals, the activity of individual dopaminergic neurons (DANs) ...
    • Multivoxel Pattern Analysis Reveals Auditory Motion Information in MT+ of Both Congenitally Blind and Sighted Individuals 

      Strnad, Lukas; Peelen, Marius V.; Bedny, Marina; Caramazza, Alfonso (Public Library of Science, 2013)
      Cross-modal plasticity refers to the recruitment of cortical regions involved in the processing of one modality (e.g. vision) for processing other modalities (e.g. audition). The principles determining how and where ...
    • Perceptual Grouping and Visual Enumeration 

      Mazza, Veronica; Caramazza, Alfonso (Public Library of Science, 2012)
      We used lateralized Event-Related Potential (ERP) measures – the N2pc and CDA/SPCN components – to assess the role of grouping by target similarity during enumeration. Participants saw a variable number (0, 1, 2 or 3) of ...
    • Re-Imagining the Future: Repetition Decreases Hippocampal Involvement in Future Simulation 

      van Mulukom, Valerie; Schacter, Daniel L.; Corballis, Michael C.; Addis, Donna Rose (Public Library of Science, 2013)
      Imagining or simulating future events has been shown to activate the anterior right hippocampus (RHC) more than remembering past events does. One fundamental difference between simulation and memory is that imagining future ...
    • A Selective HDAC 1/2 Inhibitor Modulates Chromatin and Gene Expression in Brain and Alters Mouse Behavior in Two Mood-Related Tests 

      Schroeder, Frederick A.; Lewis, Michael C.; Fass, Daniel M.; Wagner, Florence F.; Zhang, Yan-Ling; Hennig, Krista M.; Gale, Jennifer; Zhao, Wen-Ning; Reis, Surya; Barker, Douglas D.; Berry-Scott, Erin; Kim, Sung Won; Clore, Elizabeth L.; Hooker, Jacob M.; Holson, Edward B.; Haggarty, Stephen J.; Petryshen, Tracey L. (Public Library of Science, 2013)
      Psychiatric diseases, including schizophrenia, bipolar disorder and major depression, are projected to lead global disease burden within the next decade. Pharmacotherapy, the primary – albeit often ineffective – treatment ...