Search
Now showing items 101-110 of 119
Dendrite Patterning as a Model for Self-Organizing Systems
(2018-01-05)
Biological systems self-organize into complex well-ordered structures and can evolve new patterns when perturbed. To identify principles underlying self-organization, I turned to the model organism C. elegans for its ...
The Mesoscale Functional Organization of Mouse Cortex During Behavior
(2018-07-09)
Visually-guided navigation engages a network of cortical areas to process sensory information and plan movements, including visual, parietal, and retrosplenial regions. These regions have been mapped based on anatomy and ...
Dynamic Reorganization of Neuronal Activity Patterns in Parietal Cortex
(2017-09-08)
Neuronal representations change as associations are learned between sensory stimuli and behavioral actions. However, it is poorly understood whether representations of learned associations stabilize or continue to change ...
All-Optical Neurophysiology in the 1-Photon Regime
(2018-05-13)
Simultaneous optical recording and optical stimulation of neuronal activity could enable faster and more comprehensive investigation of neuronal function but is hampered by underdeveloped tools. Pairs of molecular transducers ...
A Computational Approach to Analysis and Control\\of the Mammalian Circadian Oscillator
(2018-05-11)
Circadian rhythms, endogenous, entrainable, near-24 h oscillations in metabolism, are a nearly ubiquitous feature of life on Earth. Circadian rhythms function as a feedforward biological control system that reorganizes ...
Mechanisms of Intensity Encoding for Non-Image-Forming Visual Functions
(2018-01-18)
Light drives many physiological processes that exist outside conscious awareness. These ‘non-image-forming’ visual functions are typically sensitive to the overall environmental light intensity—a parameter which can vary ...
Decomposition of Olfactory Memory by Dopamine Neural Cirucit in Drosophila
(2017-05-12)
During the formation of an olfactory memory in Drosophila, the Mushroom Body (MB) receives olfactory cues (Conditioned Stimuli, CS) relayed from the antennal lobe and aversive or reward stimuli (Unconditioned Stimuli; US) ...
Functional Characterization of Netrin-1 and Its Role in CNS-PNS Boundary Maintenance in the Developing Vertebrate Brainstem
(2018-05-01)
Netrin-1 (Ntn1) has represented the archetype of diffusible guidance cues since its discovery in the 1990s. It is often depicted in a gradient emanating from the floor plate of the embryonic neural tube, through which it ...
Mechanisms of Scale Invariance in Embryonic Patterning Systems
(2018-05-10)
Embryos pattern themselves with remarkable consistency and readily adjust their patterning programs to drastic changes in embryo size. This robustness of pattern formation, termed scale invariance, requires cells to determine ...
Understanding the Algorithms Underlying Human Motor Adaptation and Motor Reinforcement Learning
(2017-05-12)
Motor learning allows us to skillfully interact with our environments and is responsible for many of our actions such as hitting a tennis serve, driving a car, or brushing teeth. Yet despite its crucial role in our everyday ...