Browsing Harvard Medical School by Author "Heideman, Marinus R."

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    • Elevated APOBEC3B Correlates with Poor Outcomes for Estrogen-Receptor-Positive Breast Cancers 

      Sieuwerts, Anieta M.; Willis, Scooter; Burns, Michael B.; Look, Maxime P.; Gelder, Marion E. Meijer-Van; Schlicker, Andreas; Heideman, Marinus R.; Jacobs, Heinz; Wessels, Lodewyk; Leyland-Jones, Brian; Gray, Kathryn P.; Foekens, John A.; Harris, Reuben S.; Martens, John W. M. (Springer US, 2014)
      Recent observations connected DNA cytosine deaminase APOBEC3B to the genetic evolution of breast cancer. We addressed whether APOBEC3B is associated with breast cancer clinical outcomes. APOBEC3B messenger RNA (mRNA) levels ...