Browsing Harvard Medical School by Author "Fujinaga, Yukako"
Now showing items 1-3 of 3
-
A Cholera Toxin B-subunit Variant That Binds Ganglioside G M1 but Fails to Induce Toxicity
Rodighiero, Chiara; Fujinaga, Yukako; Hirst, Timothy R.; Lencer, Wayne I. (American Society for Biochemistry and Molecular Biology, 2001) -
Cholera Toxin Toxicity Does Not Require Functional Arf6- and Dynamin-dependent Endocytic Pathways
Massol, Ramiro H.; Larsen, Jakob E.; Fujinaga, Yukako; Lencer, Wayne I.; Kirchhausen, Tomas (American Society for Cell Biology, 2004)Cholera toxin (CT) and related AB(5) toxins bind to glycolipids at the plasma membrane and are then transported in a retrograde manner, first to the Golgi and then to the endoplasmic reticulum (ER). In the ER, the catalytic ... -
Gangliosides That Associate with Lipid Rafts Mediate Transport of Cholera and Related Toxins from the Plasma Membrane to Endoplasmic Reticulm
Fujinaga, Yukako; Wolf, Anne A.; Rodighiero, Chiara; Wheeler, Heidi; Tsai, Billy; Allen, Larry; Jobling, Michael G.; Rapoport, Tom; Holmes, Randall K.; Lencer, Wayne I. (American Society for Cell Biology, 2003)Cholera toxin (CT) travels from the plasma membrane of intestinal cells to the endoplasmic reticulum (ER) where a portion of the A-subunit, the A1 chain, crosses the membrane into the cytosol to cause disease. A related ...