Browsing Harvard Medical School by Author "Mayeur, Claire"

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    • Inhibition of Bone Morphogenetic Protein Signal Transduction Prevents the Medial Vascular Calcification Associated with Matrix Gla Protein Deficiency 

      Malhotra, Rajeev; Burke, Megan F.; Martyn, Trejeeve; Shakartzi, Hannah R.; Thayer, Timothy E.; O’Rourke, Caitlin; Li, Pingcheng; Derwall, Matthias; Spagnolli, Ester; Kolodziej, Starsha A.; Hoeft, Konrad; Mayeur, Claire; Jiramongkolchai, Pawina; Kumar, Ravindra; Buys, Emmanuel S.; Yu, Paul B.; Bloch, Kenneth D.; Bloch, Donald B. (Public Library of Science, 2015)
      Objective: Matrix Gla protein (MGP) is reported to inhibit bone morphogenetic protein (BMP) signal transduction. MGP deficiency is associated with medial calcification of the arterial wall, in a process that involves both ...