Browsing Harvard Medical School by Author "Smith, Gaynor A."
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A Nurr1 Agonist Causes Neuroprotection in a Parkinson’s Disease Lesion Model Primed with the Toll-Like Receptor 3 dsRNA Inflammatory Stimulant Poly(I:C)
Smith, Gaynor A.; Rocha, Emily M.; Rooney, Thomas; Barneoud, Pascal; McLean, Jesse R.; Beagan, Jonathan; Osborn, Teresia; Coimbra, Madeleine; Luo, Yongyi; Hallett, Penelope J.; Isacson, Ole (Public Library of Science, 2015)Dopaminergic neurons in the substantia nigra pars compacta (SNpc) are characterized by the expression of genes required for dopamine synthesis, handling and reuptake and the expression of these genes is largely controlled ...