Browsing Harvard Medical School by Keyword "exonuclease"
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A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway
(2013)The pluripotency factor Lin28 blocks the expression of let-7 microRNAs (miRNAs) in undifferentiated cells during development and functions as an oncogene in a subset of cancers1. Lin28 binds to let-7 precursor RNAs and ...