Browsing Harvard Medical School by Keyword "K27M"
Now showing items 1-1 of 1
-
Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomas
(Springer Berlin Heidelberg, 2014)Studies in pediatric high-grade astrocytomas (HGA) by our group and others have uncovered recurrent somatic mutations affecting highly conserved residues in histone 3 (H3) variants. One of these mutations leads to analogous ...