Search
Now showing items 1-4 of 4
Th2-predominant inflammation and blockade of IFN-γ signaling induce aneurysms in allografted aortas
(American Society for Clinical Investigation, 2004)
Abdominal aortic aneurysms (AAAs) cause death due to complications related to expansion and rupture. The underlying mechanisms that drive AAA development remain largely unknown. We recently described evidence for a shift ...
Tumor Necrosis Factor Receptor -1 and -2 Double Deficiency Reduces Graft Arterial Disease in Murine Cardiac Allografts
(Wiley-Blackwell, 2003)
Graft arterial disease (GAD) remains the leading cause of long‐term solid organ allograft failure. Tumor necrosis factor (TNF) promotes multiple aspects of allograft rejection via binding to type 1 (p55) and type 2 (p75) ...
AGE-BSA decreases ABCG1 expression and reduces macrophage cholesterol efflux to HDL
(Elsevier BV, 2007)
Background
Previous reports have suggested that advanced glycation end products (AGE) participate in the pathogenesis of diabetic macroangiopathy. However, current understanding of the mechanisms by which AGE may accelerate ...
Characterization of smooth muscle-like cells in circulating human peripheral blood
(Elsevier BV, 2006)
Smooth muscle cells play an important role in human vascular diseases. Several lines of evidence demonstrate that circulating smooth muscle precursor cells contribute to intimal hyperplasia in animal models. We obtained ...