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Now showing items 11-20 of 24
What Drives the US and Peruvian HIV Epidemics in Men Who Have Sex with Men (MSM)?
(Public Library of Science, 2012)
In this work, we estimate the proportions of transmissions occurring in main vs. casual partnerships, and by the sexual role, infection stage, and testing and treatment history of the infected partner, for men who have sex ...
Effectiveness of Patient Adherence Groups as a Model of Care for Stable Patients on Antiretroviral Therapy in Khayelitsha, Cape Town, South Africa
(Public Library of Science, 2013)
Background: Innovative models of care are required to cope with the ever-increasing number of patients on antiretroviral therapy in the most affected countries. This study, in Khayelitsha, South Africa, evaluates the ...
Closing the Gap: Increases in Life Expectancy among Treated HIV-Positive Individuals in the United States and Canada
(Public Library of Science, 2013)
Background: Combination antiretroviral therapy (ART) has significantly increased survival among HIV-positive adults in the United States (U.S.) and Canada, but gains in life expectancy for this region have not been well ...
Association of pol Diversity with Antiretroviral Treatment Outcomes among HIV-Infected African Children
(Public Library of Science, 2013)
Background: In HIV-infected children, viral diversity tends to increase with age in the absence of antiretroviral treatment (ART). We measured HIV diversity in African children (ages 6–36 months) enrolled in a randomized ...
Development, Calibration and Performance of an HIV Transmission Model Incorporating Natural History and Behavioral Patterns: Application in South Africa
(Public Library of Science, 2014)
Understanding HIV transmission dynamics is critical to estimating the potential population-wide impact of HIV prevention and treatment interventions. We developed an individual-based simulation model of the heterosexual ...
Laboratory and Clinical Predictors of Disease Progression following Initiation of Combination Therapy in HIV-Infected Adults in Thailand
(Public Library of Science, 2012)
Background: Data on determinants of long-term disease progression in HIV-infected patients on antiretroviral therapy (ART) are limited in low and middle-income settings. Methods: Effects of current CD4 count, viral load ...
Long-Term Hepatitis B Virus (HBV) Response to Lamivudine-Containing Highly Active Antiretroviral Therapy in HIV-HBV Co-Infected Patients in Thailand
(Public Library of Science, 2012)
Background: Approximately 4 million of people are co-infected with HIV and Hepatitis B virus (HBV). In resource-limited settings, the majority of HIV-infected patients initiate first-line highly active antiretroviral therapy ...
Searching for Sharp Drops in the Incidence of Pandemic A/H1N1 Influenza by Single Year of Age
(Public Library of Science, 2012)
Background: During the 2009 H1N1 pandemic (pH1N1), morbidity and mortality sparing was observed among the elderly population; it was hypothesized that this age group benefited from immunity to pH1N1 due to cross-reactive ...
HIV-1 Subtypes and Recombinants in Northern Tanzania: Distribution of Viral Quasispecies
(Public Library of Science, 2012)
This study analyzed the distribution and prevalence of HIV-1 subtypes, multiplicity of HIV-1 infection, and frequency of inter-subtype recombination among HIV-1-infected female bar and hotel workers in Moshi, Kilimanjaro ...
Factors Associated with Self-Reported Repeat HIV Testing after a Negative Result in Durban, South Africa
(Public Library of Science, 2013)
Background: Routine screening for HIV infection leads to early detection and treatment. We examined patient characteristics associated with repeated screening in a high prevalence country. Methods: We analyzed data from a ...