Browsing HMS Theses and Dissertations by Title
Now showing items 45-64 of 506
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BAD NEWS BETTER: LEARNING BREAKING BAD NEWS DURING THE TIME OF A PANDEMIC
(2021-07-19)The COVID-19 pandemic has changed the medical education landscape. Medical educators have been faced with unique challenges in providing medical students with authentic learning experiences under unprecedented circumstances. A ... -
Behavior and Characteristics of Squamous Cell Carcinoma of the Perianal Region: A Pilot Study
(2015-06-05)Introduction: We believe perianal Squamous Cell Carcinoma (SCC) is not well represented by current American Joint Committee on Cancer (AJCC) staging guidelines. We thus propose a modified staging system to better predict ... -
Best Practices in Teaching Endoscopy According to a Delphi Survey of Gastroenterology Fellows and a Pilot Study of an Instructional Checklist at a Major Academic Medical Center
(2021-09-20)Endoscopy is a core component of gastroenterology (GI) fellowship training, yet there are no guidelines on how to teach the procedure. Previously, we surveyed a national cohort of GI fellowship program directors and ... -
Better Evidence: Assessing the Utility of an Evidence-Based Clinical Resource in Two African Medical Schools
(2018-05-15)Background: Evidence-based clinical resources (EBCRs) have the potential to improve diagnostic and therapeutic accuracy at the point of care. The majority of U.S. teaching medical institutions have integrated them into ... -
Biomechanical Analyses of Novel Techniques for Knee Meniscus Repair and Proximal Subpectoral Biceps Tenodesis
(2015-06-17)Background: Many all-inside suture-based devices are currently available, including the Meniscal Cinch, FasT-Fix, Ultra FasT-Fix, RapidLoc, MaxFire, and CrossFix System. These different devices have been compared in various ... -
Biosocial Analysis of Migration and Health in Mexico, LAC and Beyond: Exploring the Right to Health for People on the Move Before, During and Beyond the COVID-19 Pandemic
(2021-06-25)Introduction: If people have been on the move for over 200,000 years, why is it that migrant’s access to healthcare continues to be a challenge? Despite global commitments to ‘leaving no one behind’, governments and ... -
BRAIN DIFFERENCES IN AUTISM SPECTRUM DISORDER
(2021-05-21)Identifying brain abnormalities in autism spectrum disorder (ASD) is critical for early diagnosis and intervention. A novel method Inception 3D-ResNet (iResNet) has been applied to identify brain structural brain differences ... -
Brain lesion and lesion network analyses of anterograde and retrograde amnesia
(2023-05-11)This thesis investigates lesion location and lesion network analyses in anterograde and retrograde amnesia using a systematic review of amnesia case reports and case series in the published peer-reviewed medical literature. ... -
Brief Surgical Procedure Code Lists for Outcomes Measurement and Quality Improvement in Resource-Limited Settings
(2016-05-17)Conditions amenable to surgery represent a significant portion of the burden of disease worldwide, accounting for 10% of deaths and 14% of disability-adjusted life years lost. Today, however, over five billion people ... -
Building a Better Babcock: A Memoir of Innovations Pursued at Harvard Medical School
(2018-05-15)Introduction: I entered Harvard Medical School at considerable short-term cost. As a mid-career military officer working at the Pentagon, I was accustomed to a standard of living somewhat above the typical medical school ... -
Buprenorphine Treatment for Opioid Addiction in the Primary Care Setting: Predictors of Treatment Success and Failure
(2015-06-08)Buprenorphine is a partial mu-opioid agonist with well-demonstrated efficacy in the medical treatment of opioid addiction. Little is known about which patients respond successfully to treatment with buprenorphine. To help ... -
Capacity Building in Urban Mongolia: Evaluating Optimal Strategies to Improve Pediatric Medical Training From Abroad
(2015-06-08)This paper, a needs assessment, represents the first-order objective of larger project to enhance post-graduate education and patient outcomes at the National Center for Maternal and Child Health in Ulaanbaatar, Mongolia ... -
Carbon Monoxide Modulates the Innate Immune Response to Bacterial Lung Infection
(2018-05-16)Carbon monoxide (CO) is generated endogenously in all mammalian cells by the enzyme Heme Oxygenase-1 (HO-1). HO-1 is primarily responsible for heme metabolism but is also vital for the host’s ability to appropriately respond ... -
CARDIAC REHABILITATION UTILIZATION AND CARDIOVASCULAR HEALTH PROMOTION
(2021-05-14)Cardiac Rehabilitation (CR) is a multidisciplinary and comprehensive outpatient secondary prevention program. Its substantial secondary prevention benefits grant it a strong recommendation for multiple indications (Balady ... -
Cardiovascular Disease in Chronic Kidney Disease
(2018-05-23)Cardiovascular disease (CVD) remains the leading cause of death in both developed and developing countries. With more than 92 million Americans with at least one type of CVD, cardiovascular causes explain up to one-third ... -
Categorizing the dispersion of open chromatin usage patterns of Treg related genes using an variational autoencoder based algorithm
(2023-05-10)Cellular programs are controlled by the coordinated interactions between transcription factors (TF) and cis-regulatory genomic sequences, including enhancer elements which can be far from the TF they regulate. This enables ... -
Cellularized Collagen-Membrane Lung Assist Devices for Efficient Gas Transfer
(2017-05-12)Chronic lower respiratory disease afflicts over 5% of the United States population, leading to over 145,000 deaths annually. There remains a need for safer and more durable alternatives to lung transplant for patients who ... -
Cervical Cancer Screening Preferences Among Trans-Masculine Individuals: Patient-Collected Human Papillomavirus Vaginal Swabs Versus Provider-Administered Pap Tests
(2018-05-15)Purpose: Trans-masculine (TM, i.e. persons who have a masculine spectrum gender identity but are assigned female sex at birth) individuals face disparities in cervical cancer screening rates compared to non-transgender ... -
Challenges in Celiac Disease: Improving Diagnosis and Identifying Accurate Surrogate Endpoints to Assess Mucosal Recovery
(2016-05-18)Great strides have been made improving serological screening tests to diagnose Celiac Disease (CD) and in recognizing the heterogenous presentation of CD. However, it is still vastly under-diagnosed. One in five children ... -
Change, Source, and Effect of GDF11 in Mouse Spleen
(2023-05-10)Growth differentiation factor 11 (GDF11) is a secreted ligand of the transforming growth factor-β (TGF-β) superfamily of proteins and regulates gene expression through AKT-MTORC1 pathway. GDF11 has been proposed as a ...