Browsing HMS Theses and Dissertations by Keyword "Biochemistry"
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KLF6 Mediates de novo Ornithine Synthesis and Polyamine Production in Pancreatic Ductal Adenocarcinoma
(2023-07-26)Pancreatic ductal adenocarcinoma (PDAC) is a malignancy that has one of the lowest 5-year survival rates amongst all cancers due to its aggressiveness and low progress in elucidating new therapies for this disease. A recent ... -
Metabolomic Profile Associated With Hyperglycemia And Chronic Diseases And Metabolic Homeostasis Derangement In Critical Illness: Post-hoc metabolomic cohort study of the VITdAL-ICU Trial
(2023-05-04)ABSTRACT Critical illnesses contribute to the maximum morbidity and mortality of hospitalized patients. Critical illness often results in the loss of metabolic homeostasis, characterized by the severe disruption of various ...