Browsing FAS Scholarly Articles by Author "Stadtfeld, Matthias"
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Cell Type of Origin Influences the Molecular and Functional Properties of Mouse Induced Pluripotent Stem Cells
Polo, Jose M.; Liu, Susanna; Figueroa, Maria Eugenia; Kulalert, Warakorn; Eminli, Sarah; Tan, Kah Yong; Apostolou, Effie; Stadtfeld, Matthias; Li, Yushan; Shioda, Toshihiro; Natesan, Sridaran; Wagers, Amy Jo; Melnick, Ari; Evans, Todd; Hochedlinger, Konrad (Nature Publishing Group, 2010)Induced pluripotent stem cells (iPSCs) have been derived from various somatic cell populations through ectopic expression of defined factors. It remains unclear whether iPSCs generated from different cell types are molecularly ... -
Fibroblast-Derived Induced Pluripotent Stem Cells Show No Common Retroviral Vector Insertions
Varas, Florencio; de Andres-Aguayo, Luisa; di Tullio, Alessandro; Pantano, Lorena; Notredame, Cedric; Graf, Thomas; Stadtfeld, Matthias; Maherali, Nimet Alia; Hochedlinger, Konrad (Wiley Subscription Services, Inc., A Wiley Company, 2009)Several laboratories have reported the reprogramming of mouse and human fibroblasts into pluripotent cells, using retroviruses carrying the Oct4, Sox2, Klf4, and c-Myc transcription factor genes. In these experiments the ...