Browsing FAS Scholarly Articles by Author "Bennett, Vann"
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Developmental mechanism of the periodic membrane skeleton in axons
Zhong, Guisheng; He, Jiang; Zhou, Ruobo; Lorenzo, Damaris; Babcock, Hazen P; Bennett, Vann; Zhuang, Xiaowei (eLife Sciences Publications, Ltd, 2014)Actin, spectrin, and associated molecules form a periodic sub-membrane lattice structure in axons. How this membrane skeleton is developed and why it preferentially forms in axons are unknown. Here, we studied the developmental ... -
A PIK3C3–Ankyrin-B–Dynactin pathway promotes axonal growth and multiorganelle transport
Lorenzo, Damaris Nadia; Badea, Alexandra; Davis, Jonathan; Hostettler, Janell; He, Jiang; Zhong, Guisheng; Zhuang, Xiaowei; Bennett, Vann (The Rockefeller University Press, 2014)Axon growth requires long-range transport of organelles, but how these cargoes recruit their motors and how their traffic is regulated are not fully resolved. In this paper, we identify a new pathway based on the class III ...