Browsing FAS Scholarly Articles by Author "Hojo, Hironobu"

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    • Molecular Basis for Unidirectional Scaffold Switching of Human Plk4 in Centriole Biogenesis 

      Park, Suk-Youl; Park, Jung-Eun; Kim, Tae-Sung; Kim, Ju Hee; Kwak, Mi-Jeong; Ku, Bonsu; Tian, Lan; Murugan, Ravichandran N.; Ahn, Mija; Komiya, Shinobu; Hojo, Hironobu; Kim, Nam-Hyung; Kim, Bo Yeon; Bang, Jeong K.; Erikson, Raymond L.; Lee, Ki Won; Kim, Seung Jun; Oh, Byung-Ha; Yang, Wei; Lee, Kyung S. (2014)
      Polo-like kinase 4 (Plk4) is a key regulator of centriole duplication, an event critical for the maintenance of genomic integrity. Here we showed that Plk4 relocalizes from the inner Cep192 ring to the outer Cep152 ring ...