Browsing FAS Scholarly Articles by Author "Dermitzakis, Emmanouil T."

Now showing items 1-3 of 3

    • Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines 

      Yelensky, Roman; Bonakdar, Sasha; Wolfish, Cara S.; Cotsapas, Chris; Rivas, Manuel; Dermitzakis, Emmanouil T.; Choy, Edwin; Plenge, Robert M.; Saxena, Richa; De Jager, Philip Lawrence; Shaw, Stanley Yang; Slavik, Jacqueline Marie; Cahir-McFarland, Ellen D.; Kieff, Elliott D.; Hafler, David A.; Daly, Mark Joseph; Altshuler, David Matthew (Public Library of Science, 2008)
      Lymphoblastoid cell lines (LCLs), originally collected as renewable sources of DNA, are now being used as a model system to study genotype–phenotype relationships in human cells, including searches for QTLs influencing ...

    • Genomic Variation and Its Impact on Gene Expression in Drosophila Melanogaster 

      Massouras, Andreas; Waszak, Sebastian M.; Albarca-Aguilera, Monica; Hens, Korneel; Holcombe, Wiebke; Ayroles, Julien; Dermitzakis, Emmanouil T.; Stone, Eric A.; Jensen, Jeffrey D.; Mackay, Trudy F. C.; Deplancke, Bart (Public Library of Science, 2012)
      Understanding the relationship between genetic and phenotypic variation is one of the great outstanding challenges in biology. To meet this challenge, comprehensive genomic variation maps of human as well as of model ...

    • Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases 

      Yang, Jialiang; Huang, Tao; Petralia, Francesca; Long, Quan; Zhang, Bin; Argmann, Carmen; Zhao, Yong; Mobbs, Charles V.; Schadt, Eric E.; Zhu, Jun; Tu, Zhidong; Ardlie, Kristin G.; Deluca, David S.; Segrè, Ayellet V.; Sullivan, Timothy J.; Young, Taylor R.; Gelfand, Ellen T.; Trowbridge, Casandra A.; Maller, Julian B.; Tukiainen, Taru; Lek, Monkol; Ward, Lucas D.; Kheradpour, Pouya; Iriarte, Benjamin; Meng, Yan; Palmer, Cameron D.; Winckler, Wendy; Hirschhorn, Joel; Kellis, Manolis; MacArthur, Daniel G.; Getz, Gad; Shablin, Andrey A.; Li, Gen; Zhou, Yi-Hui; Nobel, Andrew B.; Rusyn, Ivan; Wright, Fred A.; Lappalainen, Tuuli; Ferreira, Pedro G.; Ongen, Halit; Rivas, Manuel A.; Battle, Alexis; Mostafavi, Sara; Monlong, Jean; Sammeth, Michael; Mele, Marta; Reverter, Ferran; Goldman, Jakob; Koller, Daphne; Guigo, Roderic; McCarthy, Mark I.; Dermitzakis, Emmanouil T.; Gamazon, Eric R.; Konkashbaev, Anuar; Nicolae, Dan L.; Cox, Nancy J.; Flutre, Timothée; Wen, Xiaoquan; Stephens, Matthew; Pritchard, Jonathan K.; Lin, Luan; Liu, Jun; Brown, Amanda; Mestichelli, Bernadette; Tidwell, Denee; Lo, Edmund; Salvatore, Mike; Shad, Saboor; Thomas, Jeffrey A.; Lonsdale, John T.; Choi, Christopher; Karasik, Ellen; Ramsey, Kimberly; Moser, Michael T.; Foster, Barbara A.; Gillard, Bryan M.; Syron, John; Fleming, Johnelle; Magazine, Harold; Hasz, Rick; Walters, Gary D.; Bridge, Jason P.; Miklos, Mark; Sullivan, Susan; Barker, Laura K.; Traino, Heather; Mosavel, Magboeba; Siminoff, Laura A.; Valley, Dana R.; Rohrer, Daniel C.; Jewel, Scott; Branton, Philip; Sobin, Leslie H.; Qi, Liqun; Hariharan, Pushpa; Wu, Shenpei; Tabor, David; Shive, Charles; Smith, Anna M.; Buia, Stephen A.; Undale, Anita H.; Robinson, Karna L.; Roche, Nancy; Valentino, Kimberly M.; Britton, Angela; Burges, Robin; Bradbury, Debra; Hambright, Kenneth W.; Seleski, John; Korzeniewski, Greg E.; Erickson, Kenyon; Marcus, Yvonne; Tejada, Jorge; Taherian, Mehran; Lu, Chunrong; Robles, Barnaby E.; Basile, Margaret; Mash, Deborah C.; Volpi, Simona; Struewing, Jeff; Temple, Gary F.; Boyer, Joy; Colantuoni, Deborah; Little, Roger; Koester, Susan; Carithers, NCI Latarsha J.; Moore, Helen M.; Guan, Ping; Compton, Carolyn; Sawyer, Sherilyn J.; Demchok, Joanne P.; Vaught, Jimmie B.; Rabiner, Chana A.; Lockhart, Nicole C. (Nature Publishing Group, 2015)
      Aging is one of the most important biological processes and is a known risk factor for many age-related diseases in human. Studying age-related transcriptomic changes in tissues across the whole body can provide valuable ...